abstract：BACKGROUND AND PURPOSE:Cerebral microbleeds (CMBs) are a possible predictor of symptomatic intracranial hemorrhage (sICH) and poor function outcome (PFO). We aimed to investigate the presence of CMBs on increased incidence of sICH and PFO in acute ischemic stroke patients receiving intravenous thrombolysis (IVT) treatm...

journal_title：Journal of neurology

authors： Yan J,Qiu J,Wu X,Ge Y,Wang J,Wang Y

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The symptomatic treatment of myotonia and myalgia in patients with dystrophic and non-dystrophic myotonias is often not satisfactory. Some patients anecdotally report symptoms' relief through consumption of cannabis. METHODS:A combination of cannabidiol and tetrahydrocannabinol (CBD/THC) was prescribed as c...

journal_title：Journal of neurology

authors： Montagnese F,Stahl K,Wenninger S,Schoser B

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The efficacy and safety of mechanical thrombectomy (MT) for M2 segment occlusion of middle cerebral artery in patients with acute ischemic stroke (AIS) was investigated. METHODS:We searched PubMed and EMBASE from inception to 16 April 2019 for relevant studies, calculated the pool relative risks...

journal_title：Journal of neurology

authors： Wang J,Qian J,Fan L,Wang Y

更新日期：2020-01-22 00:00:00

abstract：BACKGROUND AND OBJECTIVE:To identify the most responsive and sensitive clinical outcome measures in GNE myopathy. METHODS:ClinBio-GNE is a natural history study in GNE myopathy. Patients were assessed prospectively by clinical, functional and quantitative nuclear magnetic resonance imaging (qNMRI) evaluations. Strengt...

journal_title：Journal of neurology

authors： Gidaro T,Reyngoudt H,Le Louër J,Behin A,Toumi F,Villeret M,Araujo ECA,Baudin PY,Marty B,Annoussamy M,Hogrel JY,Carlier PG,Servais L

更新日期：2020-01-01 00:00:00

abstract：:Alien limb syndrome following stroke within the territory of the posterior cerebral artery is exceedingly rare. A right-handed female experienced left homonymous hemianopia, visuospatial neglect, and proprioceptive loss of her left hemi-body. She experienced unintended, involuntary movements of her left arm and hand, ...

journal_title：Journal of neurology

authors： Nowak DA,Engel A,Leutbecher M,Zeller C

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Propranolol is recommended as first-line treatment for preventing migraine attacks; acupuncture has not been compared with propranolol in a head-to-head trial. OBJECTIVE:To compare acupuncture with propranolol using indirect treatment comparison meta-analysis. METHOD:We searched MEDLINE, EMBASE, and Cochra...

journal_title：Journal of neurology

authors： Chen YY,Li J,Chen M,Yue L,She TW,Zheng H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The epidemiology of paraneoplastic neurological syndromes (PNS) remains to be defined. We present here the first population-based incidence study and report the clinical spectrum and antibody profile of PNS in a large area in Northeastern Italy. METHODS:We performed a 9-year (2009-2017) population-based epi...

journal_title：Journal of neurology

authors： Vogrig A,Gigli GL,Segatti S,Corazza E,Marini A,Bernardini A,Valent F,Fabris M,Curcio F,Brigo F,Iacono D,Passadore P,Rana M,Honnorat J,Valente M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The vegetative state, also known as the unresponsive wakefulness syndrome, is one of the worst possible outcomes of acquired brain injury and confronts rehabilitation specialists with various challenges. Emergence to (minimal) consciousness is classically considered unlikely beyond 3-6 months after non-traum...

journal_title：Journal of neurology

authors： van Erp WS,Aben AML,Lavrijsen JCM,Vos PE,Laureys S,Koopmans RTCM

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Childhood arterial ischaemic stroke (AIS) is rare, but causes significant morbidity and mortality. We aimed to investigate incidence, age-dependent clinical presentation, and risk factors and to discuss the medical care situation in Germany. METHODS:This prospective epidemiological study was conducted via ES...

journal_title：Journal of neurology

authors： Gerstl L,Weinberger R,Heinen F,Bonfert MV,Borggraefe I,Schroeder AS,Tacke M,Landgraf MN,Vill K,Kurnik K,Sorg AL,Olivieri M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:To date, insertable cardiac monitors (ICMs) are the most effective method for the detection of occult atrial fibrillation (AF) in cryptogenic stroke. The overall detection rate after 12 months, however, is low and ranges between 12.4 and 33.3%, even if clinical predictors are considered. Ischemic stroke pati...

journal_title：Journal of neurology

authors： Vollmuth C,Stoesser S,Neugebauer H,Hansel A,Dreyhaupt J,Ludolph AC,Kassubek J,Althaus K

更新日期：2019-12-01 00:00:00

abstract：:Temporal lobe epilepsy has been usually associated with progressive brain atrophy due to neuronal cell loss. However, recent animal models demonstrated a dual effect of epileptic seizures with initial enhancement of hippocampal neurogenesis followed by abnormal astrocyte proliferation and neurogenesis depletion in the...

journal_title：Journal of neurology

authors： Roggenhofer E,Santarnecchi E,Muller S,Kherif F,Wiest R,Seeck M,Draganski B

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The increase in disease-modifying drugs (DMDs) allows individualization of treatment in relapsing multiple sclerosis (RMS); however, the long-term impact of different treatment sequences is not well established. This is particularly relevant for MS patients who may need to postpone more aggressive DMD strate...

journal_title：Journal of neurology

authors： Paolicelli D,Lucisano G,Manni A,Avolio C,Bonavita S,Brescia Morra V,Capobianco M,Cocco E,Conte A,De Luca G,De Robertis F,Gasperini C,Gatto M,Gazzola P,Lus G,Iaffaldano A,Iaffaldano P,Maimone D,Mallucci G,Maniscalco

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:To assess the changes of muscle-related biomarkers at the early stage of amyotrophic lateral sclerosis, and to confirm these findings in an experimental animal model. METHODS:Thirty-nine subjects with sporadic amyotrophic lateral sclerosis and 20 healthy controls were enrolled and longitudinally evaluated. W...

journal_title：Journal of neurology

authors： Ito D,Hashizume A,Hijikata Y,Yamada S,Iguchi Y,Iida M,Kishimoto Y,Moriyoshi H,Hirakawa A,Katsuno M

更新日期：2019-12-01 00:00:00

abstract：INTRODUCTION:Patients with blepharospasm in addition to involuntary contraction of the orbicularis oculi muscle also have non-motor symptoms (psychiatric, sleep, cognitive, and ocular). In this paper, we investigated the relationship of non-motor with motor symptoms and the total burden of non-motor symptoms in patient...

journal_title：Journal of neurology

authors： Ferrazzano G,Berardelli I,Conte A,Baione V,Concolato C,Belvisi D,Fabbrini G,Defazio G,Berardelli A

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:To evaluate daily life management and functional outcome of Idarucizumab administration in case of emergency situations in patients with Dabigatran treatment. DESIGN:Multicenter observational registry study. SETTING:All hospitals with full neurological departments (n = 6) in Munich, Germany INCLUDED PATIEN...

journal_title：Journal of neurology

authors： Küpper C,Feil K,Klein M,Feuerecker R,Lücking M,Thanbichler F,Dietrich D,Zerkaulen I,Jandl M,Marziniak M,Poppert H,Wunderlich S,Topka H,Dieterich M,Kellert L

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Late-onset Pompe disease (LOPD) is an often misdiagnosed inherited myopathy for which treatment exists. We noticed a bright tongue sign on brain MRIs of two patients who were admitted to the ICU for respiratory failure of unclear origin, and who were eventually diagnosed with LOPD. This led us to systematica...

journal_title：Journal of neurology

authors： Karam C,Dimitrova D,Yutan E,Chahin N

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:To characterize the clinical symptoms and magnetic resonance imaging (MRI) findings of unilateral cortical FLAIR-hyperintense Lesions in Anti-MOG-associated Encephalitis with Seizures (FLAMES). METHODS:This is a case report and systematic review of the literature to identify cases of unilateral cortical FLAM...

journal_title：Journal of neurology

authors： Budhram A,Mirian A,Le C,Hosseini-Moghaddam SM,Sharma M,Nicolle MW

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Late-onset Pompe disease (LOPD) is a rare, metabolic disease primarily affecting the musculoskeletal and respiratory systems. Forced vital capacity (FVC) is commonly used to measure pulmonary function; however, associations between FVC and other LOPD outcomes remain unclear. METHODS:A systematic literature ...

journal_title：Journal of neurology

authors： Berger KI,Kanters S,Jansen JP,Stewart A,Sparks S,Haack KA,Bolzani A,Siliman G,Hamed A

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the relationship between type II diabetes mellitus (T2DM) and ALS incidence using the National Health Insurance Research Database and Serious Disabling Disease database of Taiwan. METHODS:This was a population-based cohort study. The index date was the date of the fir...

journal_title：Journal of neurology

authors： Tsai CP,Lee JK,Lee CT

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Mal de Debarquement Syndrome (MdDS) is the rare condition of enduring rocking sensations and subjective unsteadiness following a lengthy exposure to passive motion. The pathogenesis of MdDS is unknown and the available treatment is limited. Here, we developed an experimental model of MdDS that may facilita...

journal_title：Journal of neurology

authors： Schepermann A,Bardins S,Penkava J,Brandt T,Huppert D,Wuehr M

更新日期：2019-09-01 00:00:00

abstract：INTRODUCTION:Duchenne muscular dystrophy (DMD) is induced by a wide spectrum of mutations such as exon deletions, duplications and small mutations in the dystrophin gene. This is the first study on the mutational spectrum in a cohort of DMD children from India, with an emphasis to compare the mutations in familial and ...

journal_title：Journal of neurology

authors： Polavarapu K,Preethish-Kumar V,Sekar D,Vengalil S,Nashi S,Mahajan NP,Thomas PT,Sadasivan A,Warrier M,Gupta A,Arunachal G,Debnath M,Keerthipriya MS,Pradeep-Chandra-Reddy C,Puttegowda A,John AP,Tavvala A,Gunasekaran S,S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Despite advances in the field, diagnosis and management of the wide spectrum of neurological events post allogeneic hematopoietic cell transplantation (alloHCT) remain challenging. Therefore, we investigated their incidence, diagnosis, management and long-term prognosis in alloHCT recipients. METHODS:We ret...

journal_title：Journal of neurology

authors： Sakellari I,Gavriilaki E,Papagiannopoulos S,Gavriilaki M,Batsis I,Mallouri D,Vardi A,Constantinou V,Masmanidou M,Yannaki E,Smias C,Geroukis T,Kazis D,Kimiskidis V,Anagnostopoulos A

更新日期：2019-08-01 00:00:00

abstract：OBJECTIVE:Amyotrophic lateral sclerosis type 8 (ALS8) is a familial form of motor neuron disease, with predominance of lower motor neuron degeneration, and is caused by mutation of the vesicle-associated membrane protein-associated protein B (VAPB). We aimed to compare the cognitive profile of patients with ALS8 and he...

journal_title：Journal of neurology

authors： de Alcântara C,Cruzeiro MM,França MC Jr,Camargos ST,de Souza LC

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Hyposmia can develop with age and in neurodegenerative conditions, including Parkinson's disease (PD). The University of Pennsylvania Smell Identification Test (UPSIT) is a 40-item smell test widely used for assessing hyposmia. However, in a number of situations, such as identifying hyposmic individuals in l...

journal_title：Journal of neurology

authors： Joseph T,Auger SD,Peress L,Rack D,Cuzick J,Giovannoni G,Lees A,Schrag AE,Noyce AJ

更新日期：2019-08-01 00:00:00

abstract：:Circulating and cerebrospinal fluid (CSF) neurofilament light chain (NfL) levels represent a reliable indicator of disease activity and axonal damage in different neuroinflammatory conditions. Recently, high CSF NfL levels have been detected in active autoimmune encephalitis, as opposed to significant lower levels aft...

journal_title：Journal of neurology

authors： Mariotto S,Gajofatto A,Zuliani L,Zoccarato M,Gastaldi M,Franciotta D,Cantalupo G,Piardi F,Polo A,Alberti D,Sartori S,Zanusso G,Agrò L,Demurtas R,Sechi G,Sechi E,Monaco S,Ferrari S

更新日期：2019-07-01 00:00:00

abstract：:We present evidence that Willy Loman, the protagonist of Arthur Miller's play "Death of a Salesman", meets current diagnostic criteria for probable dementia with Lewy bodies. In particular, he presents with attentional deficits and executive dysfunction (with additional subtle visuoperceptual deficits) in addition to ...

journal_title：Journal of neurology

authors： Fearon C,Taylor JP,O'Dowd S

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:Recent retrospective studies found sleep disorders, including obstructive sleep apnea and its symptoms to occur more often in patients following aneurysmal subarachnoid hemorrhage, but studies investigating the incidence of subarachnoid hemorrhage in patients with diagnosed obstructive sleep apnea [OSA] comp...

journal_title：Journal of neurology

authors： Zaremba S,Albus L,Schuss P,Vatter H,Klockgether T,Güresir E

更新日期：2019-06-01 00:00:00

abstract：:Levodopa treatment does improve Parkinson's disease (PD) dysgraphia, but previous research is not in agreement about which aspects are most responsive. This study investigated the effect of levodopa on the kinematics of writing. Twenty-four patients with PD of less than 10 years duration and 25 age-matched controls we...

journal_title：Journal of neurology

authors： Zham P,Kumar D,Viswanthan R,Wong K,Nagao KJ,Arjunan SP,Raghav S,Kempster P

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:The outcome of aphasia at 3 months is variable in patients with moderate/severe stroke. The aim was to predict 3-month aphasia outcome using prediction models including initial severity in addition to the interaction between lesion size and location at the acute phase. METHODS:Patients with post-stroke apha...

journal_title：Journal of neurology

authors： Benghanem S,Rosso C,Arbizu C,Moulton E,Dormont D,Leger A,Pires C,Samson Y

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Body weight reduction after disease onset is an independent predictor of survival in amyotrophic lateral sclerosis (ALS), but significance of weight variation after diagnosis remains to be established. OBJECTIVE:To investigate weight variation after diagnosis and its prognostic significance in patients with...

journal_title：Journal of neurology

authors： Shimizu T,Nakayama Y,Matsuda C,Haraguchi M,Bokuda K,Ishikawa-Takata K,Kawata A,Isozaki E

更新日期：2019-06-01 00:00:00

abstract：:Cluster headache (CH) is characterized by attacks of severe, strictly unilateral pain that is orbital, supraorbital, temporal, or any combination of these, lasts 15-180 min, and occurs from once every other day to eight times a day. The pain is associated with ipsilateral conjunctival injection, lacrimation, nasal con...

journal_title：Journal of neurology

authors： Ljubisavljevic S,Zidverc Trajkovic J

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:A growing number of studies have been conducted on the relationship between anger and hostility and the risk of stroke, and their conclusions are not consistent. Accordingly, we performed a meta-analysis to evaluate the relationship between anger and hostility and the risk of stroke. METHODS:We searched the ...

journal_title：Journal of neurology

authors： Chen H,Zhang B,Xue W,Li J,Li Y,Fu K,Chen X,Sun M,Shi H,Tian L,Teng W

更新日期：2019-04-01 00:00:00

abstract：: ...

journal_title：Journal of neurology

authors： Hu M,Corkill R

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Ultrafast brain MRI is required for uncooperative patients and time-critical diseases such as stroke because it reduces scan times and motion artifacts. This study investigated the clinical feasibility of a 1-min ultrafast brain MRI protocol for detecting intracranial abnormalities in restless and uncooperat...

journal_title：Journal of neurology

authors： Ryu KH,Choi DS,Baek HJ,Cho SB,Ha JY,Kim TB,Hwang MJ

更新日期：2019-02-01 00:00:00

abstract：:Autosomal recessive cerebellar ataxia type 3 (ARCA3) is a rare inherited disorder caused by mutations in the ANO10 gene. The disease is characterized by slowly progressive spastic ataxia variably associated with motor neuron involvement, epilepsy, and cognitive decline. We performed mutational screening in 80 patients...

journal_title：Journal of neurology

authors： Nanetti L,Sarto E,Castaldo A,Magri S,Mongelli A,Rossi Sebastiano D,Canafoglia L,Grisoli M,Malaguti C,Rivieri F,D'Amico MC,Di Bella D,Franceschetti S,Mariotti C,Taroni F

更新日期：2019-02-01 00:00:00

abstract：: ...

journal_title：Journal of neurology

authors： Argaet EC,Young AS,Bradshaw AP,Welgampola MS

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Since the detection of autoantibodies against neuronal surface antigens, autoimmune encephalitis (AE) has been more frequently diagnosed, especially in patients with symptoms typical of limbic encephalitis, such as seizures, short-term memory deficits, or psychosis. However, the clinical spectrum of AE may b...

journal_title：Journal of neurology

authors： Baumgartner A,Rauer S,Hottenrott T,Leypoldt F,Ufer F,Hegen H,Prüss H,Lewerenz J,Deisenhammer F,Stich O

更新日期：2019-01-01 00:00:00

abstract：:Although central facial paresis (CFP) is a major symptom of stroke, there is a lack of studies on the motor and non-motor disabilities in stroke patients. A prospective cohort study was performed at admission for inpatient rehabilitation and discharge of post-stroke phase of 112 patients (44% female, median age: 64 ye...

journal_title：Journal of neurology

authors： Volk GF,Steinerstauch A,Lorenz A,Modersohn L,Mothes O,Denzler J,Klingner CM,Hamzei F,Guntinas-Lichius O

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To report the clinical features and long-term outcome of 22 newly diagnosed paraneoplastic patients with GABAB receptor antibodies (GABABR-Abs). METHODS:Retrospective clinical study of CSF-confirmed cases of GABABR-Abs encephalitis. RESULTS:We identified 22 patients (4 female) with GABABR-Abs, with a median...

journal_title：Journal of neurology

authors： Maureille A,Fenouil T,Joubert B,Picard G,Rogemond V,Pinto AL,Thomas L,Ducray F,Quadrio I,Psimaras D,Berzero G,Antoine JC,Desestret V,Honnorat J

更新日期：2019-01-01 00:00:00

abstract：: ...

journal_title：Journal of neurology

authors： Jackson JL,Kay C,Scholcoff C,Nickoloff S,Fletcher K

更新日期：2018-12-01 00:00:00